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　　Lonnie, a crop duster pilot, must lead a mismatched group of survivors to escape the deadly zombie horde after an experimental chemical, intended to control the invasive kudzu vine, transforms the citizens of Charleston, MS into zombies.

　　阳光明媚的日子里，约翰（丹尼尔·佐瓦特 Daniel Zovatto 饰）和凯蒂（邦妮·戴尼森 Bonnie Dennison 饰）、麦特（克里斯·克罗伊 Chris Conroy 饰）、齐克（格里芬·纽曼 Griffin Newman 饰）、西蒙（约翰尼·奥希尼 Jonny Orsini 饰）和黛比（Mackenzie Rosman 饰）等五名好友，驱车来到一个毗邻湖边的僻静所在进行他们毕业前的纪念派对。他们划着小船来到湖中央，曾经有着恐怖记忆的约翰对这片水域颇多忌惮，但是他胆大妄为的伙伴们则竞相跳入水中，享受戏水的快乐时光。谁知好景不长，先是小船遭到猛烈碰撞，接着黛比被一条怪鱼咬伤致死。　　年轻人的噩梦由此展开，他们的磨难还未就此结束，嗜血猎手渐次向他们逼近……

　　In the year 2961, the time is after humanity and nature has recovered the land. A hunter named Cygnus is called to rise above his duty. He provides for Last Arc, a once nomadic band of survivors in need of food and water that is now growing scarce. The answer must be found before a group of outlandish Heretics descend upon them. Cygnus must voyage across the treacherous landscape to defend his people. Sent by Nova, the matriarch of the band, she acts based on her vision for Cygnus to find a seed of hope. The future of Last Arc is for him to discover, Cygnus ventures into a hostile landscape in search of an answer for his people. On this journey of encountering many traps and dangers, Cygnus discovers what has been hunting him is his identity.

　　公元22世纪，因为人口过度膨胀、过度开发、环境极度恶化、食物也消耗殆尽。人类想要存活下去，就必须要到宇宙中去寻找新的可以栖身的星球。因此制造了一艘当时最先进的太空飞船，去考察发现的一颗可能适宜人类生存的星球。罗伯逊（威廉·赫特 William Hurt  饰）一家被选中担负起了这次探索使命，他们将用10年的时间前往阿尔法星球。可是，这次担负起全人类命运的任务却有反对的声音，部分邪恶势力妄图阻止这次任务。所以，当罗伯逊一家驾驶太空船刚进入太空的预定轨道时，反对派史密斯博士暗中进行破坏，导致飞船脱离的正常的轨道迫降到了一颗不知名的星球上。飞船上邪恶势力的阻挠，不知名星球上的种种危机，如何才能重新设定新的航线……各种问题困惑着罗伯逊一家，他们真的就此迷失太空，无法到达目的地了吗？人类的命运将何去何从？