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　　生物学教授詹尼西尔（Pierre Brasseur 饰）因一次车祸使心爱的女儿克莉丝汀（Edith Scob 饰）面容尽毁，女儿伤愈后只能终日戴着瘆人的白色面具，痛苦非常。爱女心切且心怀内疚的詹尼西尔与助手路易丝（Alida Valli 阿莉达•瓦莉 饰）伪装克莉丝汀失踪、死亡的假象，暗中诱拐与女儿年龄相仿的女性，将其麻醉后剥掉面皮，移植到克莉丝汀脸上。　　但手术接连失败，牺牲者也不断增加。亲眼所见诸多同龄女孩惨遭杀害，克莉丝汀心中痛苦不已。另一方面，众多女孩失踪的案件也引起了警方的注意，他们逐渐将目标锁在疯狂的詹尼西尔身上……

　　Driving home late at night during a heavy rainstorm, Glen experiences car trouble. Near where his car gets stuck, he spots a house, knocks on the door and is greeted by an oddly friendly middle-aged man, Arthur, and his younger wife, Cyndi. The strange couple pours him a drink, and then more drinks, followed by an unexpected offer that Glen can’t refuse. Elsewhere, a young woman, Katie, is feeling emotionally weighed down by a secret romantic arrangement that feels like a textbook case of gaslighting. And at the same time, in a nondescript research facility, medical professional Julie begins questioning her role in a bizarre experiment, fearing that she’s doing more harm than good.

　　娜奥米-沃茨在影片中扮演一个名叫玛丽的儿童心理学家，她遭遇了人生中最不幸的事件：丈夫被一场离奇车祸夺去了性命，儿子则因这次灾难变成了植物人。一次偶然的机会，玛丽邂逅了一个叫汤姆的患儿，她将这个诡异的男孩带回家抚养，却因此招来了一连串不可思议的事件。